New drug to stop 'Ozempic butt' muscle loss side effect of obesity jabs

A new drug called apitegromab could help people on obesity jabs like Mounjaro avoid muscle loss, particularly the flattened buttocks known as 'Ozempic butt'. Research in Nature Medicine suggests that around a third of weight loss from GLP-1 drugs comes from muscle. In a six-month trial of 102 adults, those who took apitegromab maintained more muscle while still losing fat. Experts say more evaluation is needed before recommending it.